Although located completely within the city limits of El Paso, the park abounds in birds, reptiles and small mammals. The observant visitor may also catch a glimpse of mule deer, fox, and perhaps an occasional cougar. The skies above the Franklins are home to golden eagles, a variety of hawks, the occasional falcon, and come night, a variety of bats and owls. Wildlife, though secretive, is remarkably diverse.
Existing vegetation typifies the northern Chihuahuan Desert, with lechuguilla, sotol, ocotillo, several yuccas and numerous cacti. The Franklins are the only known location in Texas for a number of plant species, including the Southwest barrel cactus.